AZ developed its Best Friends Pet Joint & Immune Support with BiovaPlex® and coenzyme Q10 (ubiquinone) and special proteins. BiovaPlex® is a unique and natural joint health ingredient that contains collagen, elastin, hyaluronic acid, glucosamine, chondroitin, glycosaminoglycans as well as growth factors and elastic peptides desmosine and isodesmosine. It has been clinically demonstrated to improve activity, mobility, climbing and jumping in dogs with limited joint mobility. Dogs, like other animals (and even humans), require coenzyme Q10 as an antioxidant in mitochondrial energy metabolism and also as a broad spectrum antioxidant. Because of its antioxidant benefits, CoQ10 is reported to promote the healthy function of the heart, brain and immune system in dogs. AZ’s combination of BiovaPlex® for joints with CoQ10 for the rest of the body is the only anti-aging product of its kind for dogs.